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Holger Saal, MOSAIC KyooBe Tech

ATMPs (Advanced therapy medicinal products) – A Challenge for Cleanroom Design

5 Dec 2024

Holger Saal’s Cleanzone 2024 presentation delves into the critical challenges of commercializing cell therapies, which hold significant potential for treating various diseases but often struggle with high production costs and limited market access. The focus is on KyooBe Tech's innovative MOSAIC system, which introduces a novel approach to cell therapy manufacturing.

The MOSAIC system utilizes separate aseptic boxes, enabling the simultaneous production of cell therapies while supporting scale-out strategies. This approach not only enhances efficiency but also significantly reduces production costs. By optimizing the manufacturing process, the MOSAIC system plays a pivotal role in bridging the gap between early-stage clinical trials and large-scale production, paving the way for improved market access and greater commercial success in the field of cell therapies.

…career is a journey of innovation and technical expertise in automation and biomanufacturing. After graduating in 2011 with a degree in automation technology in production, he began his professional journey at the renowned Fraunhofer IPA, where he spent a decade driving advancements in laboratory automation and biomanufacturing. His work spanned a variety of cutting-edge life science projects, including the development of solutions for in-vitro diagnostics (IVD) and GMP-compliant facilities, establishing him as a key contributor to the field.

In 2021, Holger embraced the dynamic world of start-ups, taking on the role of CTO, where he further honed his ability to bring technical concepts to life. By late 2022, he joined KyooBe Tech as Technical Director, where he now leads the development of the company’s innovative ATMP technology, MOSAIC. This role places Holger at the forefront of redefining cell therapy manufacturing, blending his expertise in automation with a passion for transformative healthcare solutions.